*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.\
*.*.**
2. PhD at INRIA Grenoble – Rhone-Alpes, France: Stochastic Modeling and
Identification of Gene Expression Dynamics Using Fluorescence Microscopy
Data
A PhD position in the field of genetic network modelling opens at INRIA
Grenoble-Rhone-Alpes (France). The thesis focuses on the stochastic
modelling and identification of gene expression dynamics at the cell
level based on time-lapse fluorescence microscopy data. Models and
identification algorithms will be developed and tested by simulation and
by application to the study of gene expression in entero bacterium
Escherichia coli. The research activity will be conducted within the
IBIS group (http://ibis.inrialpes.fr),in tight collaboration with the
experimental biology lab of Hans Geiselmann at the Université Joseph
Fourier. The project is well suited to graduates/masters with a
background in system/control theory, computer science and probability
theory, working knowledge of scientific programming tools (e.g.,
Matlab,Scilab, C, …) and a strong interest in biological applications.
Initial gross income is 1947,80 €/month. Knowledge of French is not
requested. Application deadline is 04/05/2010.
Additional information can be found at
http://www.inria.fr/travailler/opportunites/doc.en.html(Thesis offer no
207).
Interested candidates should contact:
Eugenio Cinquemani: eugenio.cinquemani[at]inria.fr
Hidde de Jong: hidde.de-jong[at]inria.fr
*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.\
*.*.**
3. PhD at INRIA Lille, France: Observation property and observer design
for hybrid systems
One PhD position on observation of hybrid systems is open at INRIA
Lille, France. The objective of this thesis is to develop a methodology
for investigating observation property and observer design for hybrid
systems, and to study its applications. The research work will
particularly focus on applications of new techniques such as the
efficient and simple algebraic approach for numerical differentiation of
noisy signals, developed by ALIEN project-team of INRIA. The
applications linked to this topic include some of the existing hot
application fields, such as multi-agents systems, cooperative control of
mobile robots, communication based on the synchronization of chaotic
system and so on. Gross income: 1947,80 €/month. French speaking is
not necessary.
The applicants should submit their applications by the website of INRIA,
more information can be found at
http://www.inria.fr/travailler/opportunites/doc.en.html
Contributed by: gang.zheng@inria.fr
*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.\
*.*.**
4. PhD at Nancy-University, France: Data-based modeling of pesticide
water contamination from climatic events in rural catchments areas
There is an increasing use of data-based modeling and simulation in the
environmental science. The direct relationship of the rainfall with the
concentrations in pesticides is a major stake of the environment. The
objective of this project carried out in close connection with
hydologist partners is to develop new modeling techniques and tools for
the transfer of the pesticides towards water surface based on the
observation of rainfall, flow and pesticide concentrations. You will be
part of an international research environment for up to three years
while you expand your knowledge of the field and write your doctoral
thesis. This gives opportunities for many inspiring conversations, a lot
of interesting work and some travel.
The position is limited to at most three years. Usually, a PhD student
will spend about 80 percent of his or her time on graduate studies, and
about 20 percent on teaching. The position is funded by a grant of the
French National Center for Scientific Research (CNRS) and is open to
applicants of any nationality. Gross income: 2095 €/month.
Typical profiles are candidates with Master degrees in control
engineering, signal processing, computer science, environmental science
or mathematics with strong interdisciplinary interest in modeling and
simulation of environmental systems. Good programming skills (e.g.
Matlab, etc.) are also highly desirable. Teamwork and presentation
skills, as well as fluent English, are necessary requisites. French
speaking is not required.
The application deadline is 26th April 2010. The successful candidates
might be selected for an interview process in Spring and have to be
available for a start in October 2010. CV and further enquiries should
be directed to
MarionGilson: marion.gilson[at]cran.uhp-nancy.fr and
HuguesGarnier: hugues.garnier[at]cran.uhp-nancy.fr
*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.\
*.*.**
5. PhD at INRIA Sophia-Antipolis, France: Control of biological
regulatory systems: methods, design, and implementation. Application:
growth control in E. coli
The thesis will be with the COMORE team, INRIA Sophia-Antipolis. It will
address the problem of controlling the class of systems of piecewise
affine differential equations, under biologically appropriate
restrictions. Piecewise affine (PWA) differential systems constitute an
intuitive theoretical framework for the study of genetic regulatory
networks, as they are based on a qualitative description of the systems
that can be easily compared with the experimental data obtained from
gene and protein expression. In general, the parameters of PWA systems
represent synthesis and degradation rates of the molecular components of
the biological network, and the solutions represent the evolution of the
system in “rectangles”in the state space with well defined
dynamical properties. The “inputs” will be some of the synthesis
and/or degradation rates, and possible control functions will be in the
form of piecewise constant inputs to the system (constant in time
intervals or in regions of space), and ranging in a qualitative scale.
In a more advanced stage, control laws that depend on the variables of
the system or dynamic feedback laws will also be explored. Control
problems can be related to generating invariant regions, stabilization
to a given steady state, generating periodic solutions. The project will
study these control problems for small circuits (motifs such as simple
positive and negative loops, feedforward loops) and then investigate the
insertion of each motif and its control method into a larger network.
The methods developed will be applied to the genetic network that
regulates growth in E. coli (collaboration with IBIS team).
Requirements: We are looking for an applied mathematician (master
level), or computer scientist, with a background in analysis of
dynamical systems, and preferably familiar with hybrid systems theory
and/or control theory. In addition, we expect a strong motivation to
work on applications in genomics. Initial gross income is 1947,80
euros/month. Knowledge of French is not requested. Application deadline
is May 4th, 2010. Additional information and application can be found
at: http://www.inria.fr/travailler/opportunites/doc.en.html
Contact: JL Gouzé, INRIA COMORE, gouze[at]sophia.inria.fr
*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.*.\
*.*.**
6. PhD at Automatic Control Lab of Ecole Polytechnique Federale de
Lausanne (EPFL): Identification and control of an Electro Discharge
Machine
The Automatic Control Laboratory (Laboratoire d’Automatique, LA,
http://lawww.epfl.ch) of the Swiss Federal Institute of Technology in
Lausanne (EPFL) is looking for a qualified candidate for a PhD position
in the field of automatic control. The project will focus on
identification and control of an Electro Discharge Machine and is
carried out in collaboration with AG-Charmilles in Geneva.
Applicants should have a strong background in dynamical systems, signal
processing and control, and hold a master’s degree in Mechanical, or
Electrical Engineering. The position is available immediately and EPFL
offers highly competitive salaries. For application, please use the form
provided by the doctoral program in Electrical Engineering or
Manufacturing Systems and Robotics (http://phd.epfl.ch/) and send the
complete application package, indicating your intention to be hired by
LA and including 3 reference letters, to Dr. Alireza Karimi. Your
application will then be forwarded to the doctoral program directly by
LA (please pay no attention to the deadlines mentioned on the doctoral
school’s webpage).
Address:
Dr. Alireza Karimi
Laboratoire d’Automatique
EPFL -Station 9
CH-1015Lausanne, Switzerland
emai: alireza.karimi[at]epfl.ch
